C-Statin™ capsules are an all-natural nutritional supplement proven to support normal angiogenesis. Angiogenesis is the process which promotes the formation of new blood vessels. The development of new blood vessels plays a crucial role in abnormal cell growth and survival.
C-Statin contains a proprietary extract of bindweed, comprised of proteoglycan molecules (PGMs) and has no recorded adverse side effects. PGMs have been demonstrated to have significant anti-angiogenic and immunostimulatory effects. C-Statin has been shown to inhibit new blood vessel growth up to 73% and abnormal cell growth up to 96.8%.
C-Statin™ is a naturally occurring plant extract, contains a patented proteoglycan molecule (PGM) from field bindweed that is a potent angiogenesis inhibitor. Studies have demonstrated PGM to be 100 times stronger than shark cartilage.
ABSTRACT: The development of new blood vessels plays a crucial role in tumor survival and growth. Several agents that act as angiogenesis inhibitors are currently being investigated as anti-tumor agents. Proteoglycan extract (PGM) was tested for anti-angiogenic, immunostimulatory, and anti-neoplastic activity. PGM is a non-toxic extract of the ubiquitous plant, Convolvulus arvensis. In the chicken egg chorioallantoic membrane assay PGM inhibited new blood vessel growth in a dose-dependent manner. Results were 18, 55, and 73% inhibition at concentrations of 50, 100, and 200 mcg, respectively.
PGM significantly inhibited tumor growth in the mouse fibrosarcoma (S-180 Kun Ming 3-4 wk old mixed male/female, 10 animals per group, 250-1000 mcg daily doses for 14 days), and mouse Lewis lung carcinoma (C57, 6 wk old mixed male/female, 10 animals per group, 250-1000 mcg daily doses for 14 days) models.
Inhibition (54-77% inhibition by weight compared to controls, up to 96.8% by cellular composition) occurred regardless of route of administration: intravenous; intraperitoneal; subcutaneous; and oral.
PGM induced lymphocyte growth in a dose dependent manner. The ability of PGM-treated phagocytes to phagocytose yeast cells was 85% greater than controls. We conclude that PGM is a potent angiogenesis inhibitor that has immunostimulatory activity in vitro and anti-tumor activity in vivo and that PGM should be studied further as an anti-neoplastic agent.
Recommendations, Supplement facts
Take 2 tablets three times daily with water, after meals. Do not take more tablets than recommended. Do not use, if seal is broken. Store in a cool dry place. Keep out of reach of children. This dietary supplement does not replace a balanced diet.
|Servings per Container:
|Other Ingredients: Gelatin (capsule), maltodextrin.
* Share of daily requirement, ** Daily value not established.