In the Netherlands, Curcumin combi extra forte is prepared according to the international regulations for the production of drugs as food supplements. Curcumin combi extra forte is often used with patients with chronic degenerative and inflammatory diseases.
Curcumin combi extra forte contains the following ingredients:
Biocurcumin Complex – BCM95 (high-quality bio-available curcuminoids) and Polygonum cuspidatum (root extract with 50% resveratrol, pterostilbene and quercetin).
Some clinically proven effects of individual ingredients follow:
Biocurcumin BCM95 is a patented extract made from turmeric, which possesses a number of biological attributes, such as antioxidant, anti-inflammatory, antibacterial, and anti-rheumatic effects. In contrast to normal turmeric extract, Biocurcumin BCM95 possesses an extremely high bioavailability (about seven times as great). That means that an oral dosage of only 250 mg of Biocurcumin BCM95 achieve approximately the same blood-drug level as a dosage of 1,500 mg of normal turmeric extract, or about 37,500 mg of simple Curcumin Powder. Therefore, taking Biocurcumin BCM95 quickly delivers a therapeutic concentration of curcuminoids into the blood stream.
The BCM95 Complex distinguishes itself with the following positive properties:
- 100% natural turmeric extract (Curcuma longa) without added artificial ingredients
- clinical studies show that BCM95 Extract has its is bioavailability 7-8 times that of other curcumin extracts
- much smaller dosages than conventional curcumin extracts achieve the same effect
- has a powerful antioxidant effect
- has extremely good anti-inflammatory properties
From a medical standpoint, the antioxidant, anticarcinogenic, and inflammatory reducing properties of the turmeric extract are of particular interest. These properties are used in the treatment of various diseases, such as intestinal, lung, and liver diseases, and with inflammatory diseases, Alzheimer’s and heart attacks.
Japanese knotweed (Polygonum cuspidatum)
Japanese knotweed (Polygonum cuspidatum) is one of the best natural sources of resveratrol, a phytoalexin that has antioxidant and anti-inflammatory properties and which belongs to the category of polyphenols. Diverse clinical studies and animal tests with resveratrol demonstrate the positive effects of this substance on Alzheimer’s, autoimmune diseases, arteriosclerosis, and cardiovascular diseases, among other illnesses. Polyphenols are also known for their high redox potential, which makes them ideal free-radical inceptors.
It is said that resveratrol, like coenzyme Q10, directly seals the mitochondrial membrane of the so-called proton leaks and neutralizes reactive oxygen-based free radicals. Moreover, resveratrol has the capacity to stimulate the body’s own various antioxidant enzyme systems (for example, the superoxide dismutase and its own catalases). In addition, resveratrol prevents lipid peroxidation, namely the oxidation of LDL cholesterol, which in its oxidized form can be stored in the vascular wall and prepare the way for the development of arteriosclerosis. Resveratrol prevents this process and therefore counteracts the calcification of the blood vessels. Moreover, a significant neuron-protective effect is attributed to resveratrol, so that it is hoped that it can also one day be used in the treatment of Alzheimer patients.
The positive effects of resveratrol on the most diverse disorders can also be partially explained by its significant anti-inflammatory effects. This allows resveratrol to reduce two enzyme systems in the body at the same time, namely the Cyclooxygenase 2 and the intricate nitrogen monoxide synthetase, both of which play an essential role in inflammatory reaction.
Quercetin is also extracted from the so-called secondary plant matter (flavonoid) Polygonum cuspidatum. This substance has impressive antioxidant, anti-inflammatory, and immune-modulatory effects and regulates the cell cycle. Quercetin is virtually non-toxic when taken orally or intravenously. Studies from the famous Mayo Clinic and the Dana Farber Cancer Institute at Harvard University in the USA have shown that Quercetin blocks the growth of androgen-sensitive and hormone-resistant prostate cells, making them sensitive to heat; the substance is therefore suitable to support hyperthermia treatments.
Recommendations, Supplement facts
Take one capsule three times daily with water, before meals. Do not take more tablets than recommended. Do not use, if seal is broken. Store in a cool dry place. Keep out of reach of children. This dietary supplement supports healthy prostate cell function; it does not replace a balanced diet.