In the Netherlands, IMUPROS™ is prepared according to the international regulations for the production of drugs as food supplements. A specific production process makes certain that the individual ingredients in the tablets do not chemically react with one another. The individual ingredients are packed in various “time release” vessels and are released at different times into the gastro-intestinal system. In this way the release of individual ingredients into the bloodstream is optimized and the so-called bioavailability is improved. Another advantage of the product that is also worth mentioning is that it enables a drastic reduction in the daily dosage of tablets or capsules for the prevention and complementary treatment of prostate diseases. Whereas the ingredients outlined above formerly had to be individually taken in the form of 20-30 tablets or capsules daily, IMUPROS™ provides a similar effect in the easy, tolerable form of only three tablets per day. IMUPROS™ is frequently used by patients with prostate diseases, as a general complementary medicinal measure, and as supplementary therapy alongside conventional treatment.
The following are some clinically proven effects of individual ingredients:
The pharmacological effectiveness of the individual ingredients in IMUPROS™™ is widely known. In what follows, the scientifically proven effects of these individual ingredients will be addressed: tocopherolsuccinat (vitamin E), cholecalciferol (vitamin D), ascorbic acid (vitamin C), calcium, zinc, selenium (sodium selenite), genistein, lycopene, and epigallocatechin gallate:
IMUPROS™ delivers between 500 and 1,000 IU of natural vitamin E, a fat-soluble chemical substance, in the recommended daily dosage of 3-6 tablets.
Epidemiological studies have shown that vitamin D (cholecalciferol) plays a very important preventive role.
This vitamin is known for its significant antioxidant effects, which are best used in conjunction with vitamin E. It is generally recommended that 1,000 mg vitamin C be taken after eating in order to suppress the peroxide formation that arises from burning fat. Vitamin C reduces the mortality rate in coronary vascular diseases and prolongs life expectancy in patients with coronary sclerosis (British Medical Journal, 1997).
Calcium absorption must be taken into consideration with vitamin D. Excessive calcium intake (>2,000 mg per day) reduces the conversion of vitamin D into the biologically active 1.25 dihydroxycholecalciferol. Therefore, excessive calcium intake can cancel out the preventative effects of vitamin D. Everyone agrees, however, that most men do not get enough calcium. The RDA is somewhere around 1,000 mg for healthy men between 19-25 years old. IMUPROS™ contains about 470 mg of calcium in the RDA for men with prostate problems and is therefore far from the critical dosage per day.
This trace element supports a whole range of immune functions. Zinc is necessary for the normal function of many enzymes, especially those which have an antioxidant effect. When zinc levels drop in the blood stream, the NK cells, T helper cells, and immune system macrophages are suppressed.
Liang et al. (Prostate, 1999), and Iguchi et al. (Eur J Biochem, 1998) have furthermore shown that zinc can inhibit cell growth in the prostate by influencing the cell cycle, and that on top of this, tumor progression and metastasis go hand-in-hand with a drop in the ability to retain zinc in prostate cells. IMUPROS™ contains 50 mg of zinc and ensures the necessary amount of this trace element.
This mineral is just as effective at preventing prostate problems as vitamin E is.
This is a plant source of estrogen, an especially high concentration of which is found in soy and which is well known for its anti-osteoporosis and antioxidant effects. As an isoflavone, genistein also possesses the ability to help reduce cholesterol and is used as a preventative measure.
This carotenoid (which gives tomatoes their red pigment) has extremely strong antioxidant properties. It is recommended that about 15 mg of IMUPROS™ lycopene be taken per day for prevention.
This highly effective antioxidant is a polyphenol (also known as catechin) which comes from green tea (camellia sinensis). Epigallocatechin gallate (EGKG) is the most important of the four catechins in green tea for patients. EGKG inhibits the enzyme urokinase (Jankun et al.; Nature, 1997) and is also an excellent inhibitor of 5-alpha-reductase, the enzyme which causes the conversion of testosterone into biologically active dihydrotestosterone, thereby opportunely intervening in the androgen regulation of prostate cells. Consumption of green tea is widespread in Japan and China, but not so much in the West. A therapeutic dose of IMUPROS™ delivers 350 mg of EGKG per day, which amounts to about 30 cups of green tea.
IMUPROS™ is an orthomolecular combination product made from various medicinal plants and of select vitamins, minerals, and trace elements which help maintain healthy prostate function and prevent prostate diseases.
IMUPROS™ has the following effects:
- Neutralizes free radicals by way of an antioxidant effect on prostate tissue
- Optimizes cellular renewal, reduces inflammation and risk of prostate infection, and improves urinary flow in old age
- Prevents hyperplasia of the prostate
- Strengthens the immune system (cellular resistance)
The RDA should be somewhere between 1-3 tablets. Side effects are not expected to occur at this dosage. If needed, the dosage may be increased for a short period of time.
Recommendations, Supplement facts
Take one tablet three times daily with water, before breakfast and dinner. Do not take more tablets than recommended. Do not use, if seal is broken. Store in a cool dry place. Keep out of reach of children. This dietary supplement supports healthy prostate cell function; it does not replace a balanced diet.