The following are some clinically proven effects of individual ingredients:
LinumLife (Lignane from flax seed)
LinumLife is a standardized extract from flax seeds with a high concentration of so-called lignans – secondary plant matter with a phytooestrogenic effect. Additionally, lignans have a significant antioxidant effect and generally serve to keep cells healthy. Lignans also have a positive effect on benign prostate enlargement; they reduce the size of the prostate gland. The lignans in LinumLife are clinically tested, safe, and easily tolerated.
Regrestrol-complex contains four different sterols: Beta-Sitosterol, Campo-sterol, Stigmasterol and Brassicasterol. Sterol and Sterolin are actually plant fats that can be found in very high concentration in many nuts and seeds. Sterol and Sterolin are known for their healing properties in conjunction with prostate illnesses. European researchers confirmed in the renowned magazine “The Lancet” that plant- based sterols and sterolins effectively fight prostate illnesses.
For over twenty years, urologists have been successfully using sterols and sterolins instead of chemical preparations. Additional clinical studies have shown that sterols and sterolins have important inflammation-reducing properties and thus work as a prophylactic in conjunction with inflammation and diabetes. These substances contain considerable adaptogenic properties, modulate the immune system, and protect healthy cells from being attacked by our immune system.
Due to this last characteristic, sterol and sterolin also help with auto-immune illnesses, which also plays a role in the development of prostate conditions. In a random, placebo-controlled study of 177 patients with enlarged prostate glands, the effectiveness and safety of Beta-Sitosterol was tested and found to be sound. The results from patients receiving treatment with Beta-Sitosterol were much better than those of the control group, which received a placebo. Prostate illnesses declined greatly, and quality of life improved significantly.
Biocurcumin BCM95 is a patented extract made from turmeric, which possesses a number of biological effects, such as antioxidants, anti-inflammatory, antibacterial, and anti- rheumatic effects. In contrast to normal turmeric extract, Biocurcumin BCM95 possesses an extremely high bioavailability (about seven times as great). That means that an oral dosage of only 250 mg of Biocurcumin BCM95 produces approximately the same blood-drug level as a dosage of 1,500 mg of normal turmeric extract, or about 37,500 mg of simple Curcumin Powder. Therefore, taking Biocurcumin BCM95 quickly delivers a therapeutic concentration of curcuminoids into the blood stream.
The BCM95® Complex positively distinguishes itself with the following properties:
- 100% natural turmeric extract (Curcuma longa) without added artificial ingredients
- clinical studies show that BCM95 Extract has a bioavailability that is seven to eight timesbetter than other Curcumin extracts
- much smaller dosages are required to achieve the same effect of conventional curcuminextracts
- has a powerful antioxidant effect
- has extremely good anti-inflammatory propertiesFrom a medical standpoint, the antioxidant, anti-carcinogenic, and the inflammatory reducing properties of the turmeric extract are of particular interest.
These properties are used in the treatment of various diseases, such as intestinal, lung, and liver diseases, and with inflammatory diseases, Alzheimer’s and heart attacks.
Saw palmetto (Serenoa Repens)
The healing property of the lipophilic extract of the fruit of the saw palmetto (Serenoa repens) in conjunction with prostate illnesses has long been known. Randomized double-blind studies have shown that saw palmetto extract is effective with benign prostate enlargement at a dose of 320 mg per day and that it greatly improves urinary and bladder function. The maximum, as well as the average urinary flow rate improved upon taking this extract. In comparison to the usual synthetic substances containing finasteride, saw palmetto has at least the same effectiveness with fewer side effects, is better tolerated, and the treatment is also much more cost-effective. Saw palmetto research has concentrated on its application in prostate treatment. Aside from positive effects on benign prostate issues, saw palmetto also has a proven effect in conjunction with prostate problems. It hinders, for instance, cell proliferation in prostate tissue and supports the normal programmedcell death (apoptosis) of cells.
Recently ginsenosid and saponin, the pharmacological properties in ginseng root, have been used in Europe, although the healing properties of the ginseng root in conjunction with numerous diseases have been long known primarily in China and other Asiatic countries.
The substance saponin in particular inhibits breast and prostate cells, In prostate carcinoma, it suppresses the PSA value. It also has a positive influence on androgen receptors and on the enzyme 5- alpha-reductase.
Ginsenoid supports normal programmed cell death (apoptosis) in prostate cells and reduces the activity of so-called Bcl-2 genes. Moreover, ginsenosid restricts the process of metastasis and decreases the development of certain cells in other tissues. Lastly, ginsenosid inhibits new growth of blood vessels, which leads to growth retardation of primary tumors and of metastasis (anti-angiogenetic effect).
Baikal Skullcap (Scutellaria baicalensis)
Extract from the Scutellaria baicalensis contains the flavonoid baicalin, which causes programmed cell death (apoptosis) in DU-145 prostate cells even in very low concentration.
African prune tree (Pygeum africanum, Prunus africana)
Pygeum extract comes from the bark of a plum tree native to Africa. Since the sixties, this extract has been used successfully in the treatment of bladder and prostate problems, especially in therapy addressing benign prostatic hyperplasia. At this time, for instance, pygeum is the most important substance in the treatment of benign prostatic hyperplasia. Its effects have been proven in double- blind studies. Taking standardized pygeum extract reduces the enzyme activity of the so-called 5-alpha- reductase and inhibits inflammation so that a noticeable improvement in water solubility is perceptible. In the objective measurement of urine emission, there is improved urine flow. A multicenter study at the University of Bratislava has shown that daily intake of 100 mg of pygeum (over the course of about two months) increased quality of life and greatly improved the amount of urine per excretion. So far, research has shown no side effects from pygeum.
Reishi (Ganoderma lucidum)
Reishi mushrooms have been used for over 4000 years in Chinese medicine. The ingredients within the fruit bodies of the mushroom, such as Triterpenoide, a sterole, manitol, coumarin, and various polysaccharides, are used medicinally. Furthermore, the mushrooms contain various trace elements, such as zinc, germanium, manganese, iron, copper, and even calcium. Recent research results show that reishi mushroom extract strengthens the immune system and also demonstrates immune modulating properties. The reishi has proven itself particularly useful in the treatment of prostate illnesses, since it inhibits prostate inflammation, thereby working against prostatitis. It also suppresses cell adhesion and cell migration in prostate cells, thereby reducing tumor migration.
Japanese knotweed (Polygonum cuspidatum)
Japanese knotweed (Polygonum cuspidatum) is one of the best natural sources of resveratrol, a phytoalexin that has antioxidant and anti-inflammatory properties which belongs to the category of polyphenols.
Polyphenols are also known for their high redox potential, which makes them ideal radical inhibitors. Like coenzyme Q10, resveratrol is purported to directly seal over the mitochondria of the so-called proton leak and to neutralize reactive oxygen-based free radicals. Moreover, it has the capacity to stimulate a number of the body’s own different antioxidant enzyme systems (for example, the superoxide dismutase and some catalases).
In addition, resveratrol prevents lipid peroxidation, namely the oxidation of LDL-Cholesterol, which in its oxidized form can be stored in the vascular wall and prepare the way for the development of arteriosclerosis. Resveratrol prevents this process and therefore works against the calcification of the blood vessels. Moreover, a significant neuron-protective effect is attributed to resveratrol, so that it is hoped that it can also one day be used in the treatment of Alzheimer patients. The positive effects of resveratrol in conjunction with various disease patterns can also be partially explained by its significant anti-inflammatory effects. This allows resveratrol to reduce two enzyme systems in the body, namely the Cyclooxygenase 2 and the intricate nitrogen monoxide synthetase, both of which play an essential role in inflammatory reaction.
Quercetin is also extracted from the so-called secondary plant matter (flavonoid) Polygonum cuspidatum. This substance has impressive antioxidant, anti-inflammatory, and immune-modulatory effects and regulates the cell cycle. Quercetin is virtually non-toxic when taken orally or intravenously.