The following are some clinically proven effects of individual ingredients:
Agrimony (Argrimonia pilosa) belongs to a plant genus which is a subfamily of the rosoideae within the rose family (Rosaceae). The agrimony species is widespread in Europe and Asia and reaches as far as Sri Lanka and Java. A few types are also found in North America and Mexico. As a medicinal plant, Argrimonia pilosa has been well-known for an especially long time for its inflammation-reducing properties. Alcoholic extracts of the plant can also quickly reduce the strongest inflammation reaction. Extracts from the stem and leaves also have analgesic, antibacterial, and antipyretic effects.
Argrimonia pilosa is therefore used frequently in cases of abdominal pain, soar throat, and headaches. Extracts from the leaves have a high amount of agrimony, which increases heart function, decreases blood sugar levels, and increases blood pressure. The leaves of the plant are also rich in vitamin K, which is why Argrimonia pilosa is also used to support thrombus formation and hemostasis. Root extracts from the plant work as an astringent and diuretic and are used in the treatment of colds, tuberculosis, and diarrhea.
Round-leaved wintergreen (Pyrola rotundifolia)
Round-leaved wintergreen (Pyrola rotundifolia) is a plant from the subfamily of the wintergreen and monotropa hypopitys plants (Monotropoideae) in the heather family (Ericaceae). The leaves of this medicinal plant have anti-rheumatic, antiseptic, antispasmodic, astringent, cardiotonic, contra-ceptive, diuretic, sedative, and tonic effects. Water extracts are used locally for skin diseases, but also gurgled in conjunction with throat conditions, as well as with ulcers in the mouth. The extracts are also suitable for use in conjunction with treatments for carbuncles and painful swelling. Water extracts are also used to rinse inflamed eyes. The extract can be used internally to treat epilepsy and other illnesses of the central nervous system. Pyrola rotundifolia contains Arbutin, a diuretic that possesses an antibacterial effect, which can be of use with urinary tract infections.
Corydalis rhizome (Corydalis yanhusuo)
Extracts of Corydalis yanhusuo; (Chinese name: Yan Hu Shuo) have been used for many centuries in traditional Chinese medicine.
Alternative medicine has shown that various parts of the plant can have a positive effect on very different illnesses. For instance, some of these extracts are purported to have properties which improve blood and which ease almost every kind of pain, including cramps (spasms). Corydalis is therefore frequently used in the treatment of menstrual cramps and the pain they cause. It is also applicable for use with general stomach aches. The plant, and in particular the root extracts, contain various effective alkaloids (for instance, Bulbocapnin, Cordalin, Protopin), which are responsible for the analgesic, antispasmodic, and sedative effects. Furthermore, substances extracted from Corydalis are significantly anti-carcinogenic and have the capacity to minimize coughing, raise cardiac output, and inhibit high blood pressure.
As a result of the positive sedative effects of the alkaloid “bulbocapnin”, corydalis extract is also used in traditional Chinese medicine for the treatment of cramps such as muscle tremor and vestibular nystagmus. So it follows that patients who have Parkinson’s and Meniere’s diseases should also benefit from treatment using corydalis extract. Many studies are currently underway which look at the application of corydalis in conjunction with cancers, menstruation pain, high blood pressure, cramps, and as a natural painkiller.
Reishi (Ganoderma lucidum)
The reishi or lingzhi mushroom has been used for over 4,000 years in Chinese medicine. The ingredients within the fruit bodies of the mushroom, such as triterpenoids, steroles, manitol, coumarin, and various polysaccharides, are used medicinally. Furthermore, the mushrooms contain various trace elements, such as zinc, germanium, manganese, iron, copper, and even calcium. Recent research results show that reishi mushroom extract strengthens the immune system and also demonstrates immune modulating properties. The reishi has proven itself particularly useful in the treatment of prostate illnesses, since it inhibits prostate inflammation, thereby counteracting prostatitis. It also suppresses cell adhesion and cell migration in prostate cancer, thereby reducing tumor migration.
Red spider lily (Lycoris radiata)
Lycoris radiata, also known as “red spider lily,” belongs to the onion and tuber family, the amaryllidaceae. The plants get to be about 10 to 30 cm tall and are cultivated mostly in central and south Japan. Extracts of the tuber root are used in the treatment of swelling, ulcers, and nervous disorders in children. Contained within the flowers are two alkaloids which have an emetic and expectorant effect. Extracts from the shrubs are often used as an antidote to poison in traditional Chinese medicine. The flowers can also be made into a paste which can be applied to burns and open wounds. The anti-carcinogenic effect of the extract of lycoris radiata is due to various alkaloids, such as dehydrolycorine, bulbispermine, methylen-dioxylhomolycorine-N-oxide and dihydromethyl-hydroxy-phenanthridine, which have a very potent cytostatic and cytotoxic effect on different cancer cell cultures. Some of the alkaloids also have significant anti-malaria effects.
Patrinia (Patrinia heterophylla)
For hundreds of years, patrinia heterophylla has been used in traditional Chinese medicine for the treatment of menstrual pains, ulcer formation, liver inflammations (hepatitis), tonsillitis, and a few other medical problems. Recent research results have shown that extracts from this medicinal plant have very high anti-carcinogenic effects. Various triterpenes have been identified in Patrinia heterophylla as being the primary substances possessing an anti-carcinogenic effect. Also extracted from Patrinia heterophylla is an additional substance called isocoumarin glucoside, which demonstrates a significant capacity to fight cancer cells in the uterus. Various proteins and polysaccharides from this medicinal plant have been isolated which intervene in energy metabolism and in the signal transduction of cancer cells, reduce oxidative stress, and can trigger apoptosis (programmed cell death).
Stephania herb (Stephania sinica)
Stephania sinica belongs to the moon seed family (menispermaceae), which is native to Southeast Asia, Africa, and Australia. Stephania (menispermaceae) is widespread and has been used in folk medicine for centuries to counteract various illnesses, such as asthma, tuberculosis, diarrhea, diabetes mellitus, malaria, and cancer. More than 150 alkaloids, flavorings, lignans, steroids, terpenoids, and coumarins have been isolated in the stephania sinica herb. Many of these substances have biological activity. Anti-malaria, antiviral, antibacterial, anti-inflammatory, anti-pain, immune-modulatory, and anti-carcinogenic effects have all been attributed to it. That is why it is known that dehydrocrebanine and crebanine, two of the isolated ingredients in stephania sinica, have a significant inhibitory effect in the growth of stomach carcinoma cells, leukemia cells, and liver cancer cells.
Rabdosia (Rabdosia rubescens)
The two most important properties of this fast-growing, terpenoid-rich labiate are oridonin and rubescensin A and B, both of which are known for their cancer-inhibiting effects. Extracts made from the entire plant improve digestion, soothe inflammation, and are used primarily in China in the prevention of breast cancer and prostate carcinoma. Laboratory results show that the positive effects on breast and prostate cancer are not due to a hormonal effect, but rather to the direct influence of the cell cycle and apoptosis (direction of programmed cell death). Recent studies have also shown that oridonin inhibits the growth of primary bone cancers (multiple myeloma) and various types of leukemia by initiating apoptosis. The anti-carcinogenic effect of oridonin is also free of side effects, since healthy cells are not influenced. Rabdosia rubescens also reduces the blood supply to transplanted breast tumors and thereby inhibits the growth of those tumors. In prostate cancer, the effects of Rabdosia rubescens also inhibit the development of so-called androgen independent cancer cells, which almost always develop after prolonged anti-hormonal treatment. In this way, the effectiveness of conventional anti-hormonal therapy for prostate cancer is extended by way of Rabdosia rubescens. A study using 115 patients with inoperable esophageal cancer showed that patients who received Rabdosia Rubescens in conjunction with conventional therapy had a survival rate three times as high as patients in the comparison group, who only received chemotherapy.
Desert broomrape (Cistanche deserticola)
Desert broomrape (Chinese name: “Rou Cong Rong”) is an albino parasitic plant that has been used as a tonic in traditional Chinese and Japanese medicine for about 1800 years. Modern pharmacological research has shown that cistanche deserticola possesses a broad spectrum of biological properties. That is why it is known to have significant hormone-regulatory, immune-modulatory, neuron-protective, anti-oxidant, anti-apoptotic, anti-inflammatory, and anti-nociceptive effects. Furthermore, extracts of cistanche counteract exhaustion and promote bone growth. The so-called phenylethanoids glycoside, acteoside, echinacoside and cistanoside in cistanche deserticola seem to be responsible for these effects. Various animal experiments have shown that a polysaccharide from cistanche deserticola has immune modulatory effects which increase the phagozytose capacity of macrophages, thereby strengthening cellular defense. It has also been shown that acteoside from cistanche significantly increases the ability to swim in mice without causing muscular damage and without piling on lactate in muscles. Cistanche deserticola extracts appear to improve the muscles’ ability to store energy. The same extract has also been observed to improve both learning and memory capacity in test animals, which also increases the growth of nerve tissue. Although most of the pharmacological effects of cistanche extract have only been confirmed in lab and animal experiments, this medicinal plant is highly desirable and has been placed on the list of endangered species.
Ginseng (Panax ginseng)
Recently ginsenosid and saponin, the pharmacological properties in ginseng root, have been used in Europe, although the healing properties of the ginseng root in conjunction with numerous diseases have been long known primarily in China and other Asiatic countries. The substance saponin in particular inhibits prostate cancer cells and suppresses increase in the PSA value. It also has a positive influence on androgen receptors and on the enzyme 5-alpha-reduktase. Ginsenoid supports normal programmed cell death (apoptosis) in prostate cells and reduces the activity of so-called Bcl-2 genes, which make cells invincible thereby causing and supporting cancer. Moreover, ginsenosid restricts the process of metastasis, decreases the development of cancer cells in other tissues, and possesses an anti-angiogenic effect which reduces new vessel formation in metastases and primary tumors, thereby restricting the blood flow to tumor tissue (“starvation of the tumor”). Recent research results have shown that ginseng also has a preventative effect against various kinds of cancer and ginsenoside has a significant anti-inflammatory effect in addition to its cancer-inhibiting effect.
Shiny-leaf prickly-ash (Zanthoxylum nitidum)
Zanthoxylum nitidum is a flowering plant in the citrus family, which primarily grows in Southeast Asia and northern Australia. The Chinese name is “liang mian zhen”. Almost all zanthoxylum species are used medicinally. In India zanthoxylum is used, for example, to counteract toothache and fever and to fight coughing, vomiting, and diarrhea. In China, individual zanthoxylum species are also used to fight pain, as well as to treat stomach ailments and cancers. Nitidine, a substance in shiny-leaf prickly-ash, has been identified as effective in fighting cancer. Additionally, this substance has also been used effectively in conjunction with AIDS and malaria agents. Particular plant extracts from zanthoxylum also have antibacterial effects.
Liquorice (Glycyrrhiza glabra)
Liquorice extracts contain various saponins of glycyrretic acids, which function as expectorants and mucolytic agents and possess antibacterial and antimicrobial properties. It has also been experimentally and clinically shown that extracts from liquorice have anti-inflammatory, cramp-suppressive, and antiviral effects. An American study published in the “Journal of Clinical Investigation” has additionally shown that the glycyrretic acids in liquorice can prevent cancer by inhibiting an enzyme that is needed for cancer growth. Liquorice is used as an alternative treatment for sore throats, bronchitis, and stomach aches and for viral infections and cancer.
IMUSAN™ is a purely biological product made from extracts of various medicinal plants which have had the following effects on patients with general immunity deficiencies and various kinds of cancers:
- Strengthening of the immune system (cellular resistance)
- Inhibition of cancer growth by strengthening normal programmed cell death (apoptosis) and direct cytotoxic properties
- Neutralizes free radicals by way of an antioxidant effect
- Antiviral activity
- Anti-inflammatory property
- Pain-reduction property
The recommended daily allowance (RDA) should be between 2-3 capsules and can be increased as needed. Side effects are not expected at this dosage.