In the Netherlands, PROSTECTAN is prepared according to the international regulations for the production of drugs as food supplements. PROSTECTAN is frequently used by patients who have chronic prostatitis, with prostatic hyperplasia (benign enlargement of the prostate gland), and in complementary therapy of prostate cancer.
PROSTECTAN™ contains the following plant-based extracts:
Reishi (Ganoderma lucidum), Saw palmetto (Serenoa repens), liquorice (Glycyrrhiza glabra), Baikal Skullcap (Scutellaria baicalensis), Ginseng (Panax ginseng), Woad (Isatis tinctoria), chrysanthemum (Dendranthema morifolium), Rabdosia (Rabdosia rubescens), and Biocurcumin complex „BCM95“ with various, with high-quality, bioavailable curcuminoids and LinumLife (Lignane from flax seeds).
The following are some clinically proven effects of individual ingredients:
Reishi (Ganoderma lucidum)
The reishi or lingzhi mushroom has been used for over 400 years in Chinese medicine. The ingredients within the fruit bodies of the mushroom, such as triterpenoide, sterols, manitol, coumarin, and various polysaccharides are used medicinally. Furthermore, the mushrooms contain various trace elements, such as zinc, germanium, manganese, iron, copper, and even calcium. Recent research results show that reishi mushroom extract strengthens the immune system and also demonstrates immune modulating properties. The reishi has proven itself particularly useful in the treatment of prostate illnesses, since it inhibits prostate inflammation, thereby counteracting prostatitis. It also suppresses cell adhesion and cell migration in prostate cancer, thereby reducing tumor migration.
Saw palmetto (Serenoa Repens)
The healing properties of the lipophilic extract of the fruit from the saw palmetto (Serenoa repens) in the treatment of prostate illnesses have long been known. Randomized double-blind studies have shown that saw palmetto extract is effective with benign prostate enlargement at a dose of 320 mg per day and that it greatly improves urinary and bladder function. The maximum, as well as the average urinary flow rate improved upon taking this extract. In comparison to the usual synthetic substances containing finasteride, saw palmetto has at least the same effectiveness with fewer side effects, is better tolerated, and the treatment is also much more cost-effective. Saw palmetto research has concentrated on its application in prostate treatment. Aside from positive effects on benign prostate issues, saw palmetto also has a proven effect in the treatment of prostate cancer. It hinders, for instance, cell proliferation in prostate cancer tissue and supports the normal programmed cell death (apoptosis) of cancer cells.
Liquorice (Glycyrrhiza glabra)
Liquorice extracts contain various saponins of glycyrretic acids, which function as expectorants and mucolytic agents, as well as possessing antibacterial and antimicrobial properties. Experimentally and clinically, it is also known that extracts from liquorice have anti-inflammatory, cramp-suppressive, and antiviral effects. An American study published in the “Journal of Clinical Investigation”, has also shown that the glycyrretic acids in liquorice can prevent cancer by inhibiting an enzyme that is needed for cancer growth. Liquorice is used as an alternative treatment for sore throats, bronchitis, and stomachaches, as well as for viral infections and cancer.
Scutellaria Baicalensis (Baikal Skullcap)
Extract from Scutellaria Baicalensis contains the flavonoid baicalin, which causes programmed cell death (apoptosis) in DU-145 prostate cancer even in very low concentration. That is why researchers at the molecular biological center at Valhalla University in New York were able to show in studies on prostate cancer cell cultures that scutellaria extract causes a reduction in cancer cell growth by about 60% and curbs PSA production in these cells. Baicalin hinders cell growth in many other types of tumors as well. These include lung and colorectal cancers and brain tumors. Under the influence of the flavonoid baicalin, cell division is inhibited and normal programmed cell death (apoptosis) is supported. Russian researchers have been able to prove that baicalin has a positive effect on blood renewal, improving blood flow in bone marrow in patients with tumor-induced anemia and also minimizes the side effects of chemotherapy.
Ginseng (Panax ginseng)
Recently ginsenoside and saponin, the pharmacological effects in ginseng root, have been used in Europe, although the healing properties of the ginseng root in the treatment of numerous diseases have been long known primarily in China and other Asiatic countries. The substance saponin in particular inhibits prostate cancer cells and suppresses increase in PSA value. It also has a positive influence on androgen receptors and on the enzyme 5-alpha-reductase. Ginsenoside supports normal programmed cell death (apoptosis) in prostate cells and reduces the activity of so-called Bcl-2 genes, which make cells invincible, thereby causing and supporting cancer. Moreover, ginsenoside restricts the process of metastasis, decreases the development of cancer cells in other tissues, and possesses an anti-angiogenic effect which reduces new vessel formation in metastases and primary tumors, thereby restricting the blood flow to tumor tissue (“starvation of the tumor”). Recent research results have shown that ginseng also has a preventative effect against various kinds of cancer and ginsenoside has a significant anti-inflammatory effect in addition to its cancer-inhibiting effect.
Woad (Isatis tinctoria or indigotica)
Woad is a biennial plant in the mustard family. The roots and parts of the trunk have been used for hundreds of years in traditional Chinese medicine for patients with a variety of tumors. Isatis indigotica has tumor-active substances in all parts of the plant. One of these substances is indirubin, which inhibits an important cell cycle enzyme in the tumor cell, namely, the so-called “cyclin”-dependent kinase, and in so doing, significantly reduces the growth of breast and prostate cancer cells, for instance. The aqueous extract of parts of the plant are purported to help hinder tumor development and proliferation. Mild side effects, such as rare allergic reactions and light dizziness, occur with very high doses.
Rabdosia (Rabdosia rubescens)
The two most important properties of this quickly growing, terpenoid-rich labiate are oridonin and rubescensin a and b, both of which are known for their cancer-inhibiting effects. Extracts made from the entire plant improve digestion, soothe inflammation, and are used primarily in China in the prevention of breast cancer and prostate carcinoma. Laboratory results show that the positive effects on breast and prostate cancer do not occur due to a hormonal effect, but rather by way of direct influence of the cell cycle and apoptosis (direction of programmed cell death). Recent studies have also shown that oridonin inhibits the growth of primary bone cancers (multiple myeloma), as well as various types of leukemia by initiating apoptosis. The anti-carcinogenic effect of oridonin is also free of side effects, since healthy cells are not influenced. Rabdosia rubescens also reduces the blood supply to transplanted breast tumors and thereby inhibits the growth of those tumors. In prostate cancer, the effects of Rabdosia rubescens also inhibit the development of so-called “androgen independent cancer cells”, which almost always develop after prolonged anti-hormonal treatment. In this way, the effectiveness of conventional anti-hormonal therapy for prostate cancer is extended by way of Rabdosia rubescens. A study using 115 patients with inoperable esophageal cancer showed that patients who received Rabdosia Rubescens in conjunction with conventional therapy had a survival rate three times that of patients in the control group, who only received chemotherapy.
Chrysanthemum (Dendranthema morifolium)
Extract from the chrysanthemum flower (Dendranthema morifolium) contains triterpendiole and triterpentriole. In a study at the National Cancer Institute (NCI) in the USA, it was shown that one of these substances, namely arnidiol, was extremely effective in fighting 58 of 60 kinds of cancer cells. The substance killed these cancer cells in the lab within a short amount of time and thereby also showed an “additive effect” in combination with Rabdosia rubescens. In traditional Chinese medicine, the healing properties of chrysanthemum flowers have been known for a few thousand years. In this tradition the extract of chrysanthemum flower leaves are purported to improve eyesight, eliminate headaches, and have calming, anti-bacterial, anti-fungal, and anti-inflammatory properties. The coronary arteries are also purportedly enlarged by chrysanthemum extract, which improves overall cardiovascular function.
Biocurcumin BCM95 is a patented extract made from turmeric, which possesses a number of biological effects, such as anti-oxidant, anti-inflammatory, antibacterial, and anti-rheumatic effects. Additionally, this curcumin extract has a significant anti-carcinogenic effect which acts on many different kinds of tumors. Biocurcumin BCM95 has 7-8 times better bioavailability than other Curcumin extracts. That means that with an oral dosage of only 250 mg of Biocurcumin BCM95, approximately the same blood-drug level is achieved as in a dosage of 1,500 mg of normal turmeric extract, or about 37,500 mg of simple Curcumin Powder. Therefore, taking Biocurcumin BCM95 quickly delivers a therapeutic concentration of curcuminoids into the blood stream.
The BCM95 Complex positively distinguishes itself with the following properties:
- 100% natural turmeric extract (Curcuma longa) without added artificial ingredients
- clinical studies show that BCM95 Extract has a 7-8 times better bioavailability than other Curcumin extracts
- achieves the same effect as that produced by high doses of conventional curcumin extracts with much smaller doses
- has a powerful antioxidant effect
- has extremely good anti-inflammatory properties
From a medical standpoint, the antioxidant, anti-carcinogenic, and inflammatory-reducing properties of turmeric extract are of particular interest. These properties are used in the treatment of various diseases, such as intestinal, lung, and liver diseases, as well as with inflammatory diseases, Alzheimer’s, heart attack, and cancer illnesses. Clinical tests and studies conducted on animals confirm in particular the cancer-reducing property in the treatment of stomach, intestinal, liver, and skin cancer. Even advanced metastasis development can be considerably reduced by using curcumin.
LinumLife (Lignans from flax seed)
LinumLife is a standardized extract from flax seeds with a high concentration of so-called lignans – secondary plant compound with a phyto-oestrogenic effect. The lignans have a pharmaceutical rather than a nutritional effect, characterized by powerful antioxidant- and low oestrogenic activity, which serve to keep cells healthy while also preventing cancer. A scientific report from the Cancer Institute in Heidelberg from 2004 recommended using flax seed oil and flax seeds in the prevention of breast and colon cancer. Lignans also have a positive effect on benign prostate enlargement reducing the size of the prostate gland. LinumLife is clinically tested, safe, and well tolerated.